When a patient comes to you, they bring more than just a symptom. They bring a story. This story holds the key to understanding what is wrong. The most advanced scans and lab tests in the world are only helpful when they are guided by a clear, complete story from the patient. Your most vital skill, therefore, is not operating a machine, but knowing how to listen and ask the right questions.
To get this complete story every single time, you cannot rely on random questions. You need a structured approach. In medicine, gathering this story is called taking the “history of present illness,” or HPI. A strong HPI is the cornerstone of every diagnosis and treatment plan. The best way to build a perfect HPI is to use a simple, reliable framework. That framework is called OLD CARTS.
OLD CARTS is a history-taking mnemonic and an easy-to-remember acronym. Each letter stands for an essential part of the patient’s experience: Onset, Location, Duration, Character, Aggravating factors, Relieving factors, Timing, and Severity. Think of it as your comprehensive guide. It ensures you collect every piece of information you need, without missing anything important. This blog will walk you through each part of OLD CARTS using simple language. You will learn why each piece is crucial and how using this framework helps you provide the best possible care for every patient.
O is for ONSET – When and How Did It All Start?
What Does “Onset” Really Mean?
Onset asks one simple question: When did this problem begin? But it is not just about the date. It is about the circumstances. Think of it like the first scene of a movie. Did the problem start suddenly, like a gunshot? Or did it creep in slowly, like a fog rolling in over several weeks?
- Sudden Onset: “The chest pain hit me while I was shoveling snow ten minutes ago.” This is a red flag. It suggests something acute, like a heart attack, a blood clot, or a rupture. It tells you this needs urgent attention.
- Gradual Onset: “I’ve noticed my knee getting stiffer over the last few months.” This points to a chronic issue, like osteoarthritis or a slow-growing problem.
The “How” is as Important as the “When”
You must also ask, “What were you doing when it started?” This links the symptom to an activity or event.
- Did the back pain start right after lifting a heavy box? That suggests a muscle strain.
- Did the headache begin after a long day at the computer? That might point to tension or eye strain.
- Did the abdominal pain start after a specific meal?
The onset gives you the starting point of your timeline. It helps you decide if this is an emergency or a long-term issue. Without knowing the onset, you are trying to understand a problem without knowing when it began.
L is for LOCATION – Where in the Body is the Problem?
Finding the Epicenter
Location means: Where exactly do you feel it? Our first job is to get the patient to point to the spot. A patient saying “my stomach hurts” is not enough. Is it the upper right part? The lower left? The center?
Ask them to use one finger to show you the exact place. This simple act can make a big difference. Pain in the right lower abdomen is classic for appendicitis. Pain in the center of the chest that spreads to the left arm raises concern for the heart.
Does It Stay or Does It Move?
The next critical question is: “Does the pain stay in that one place, or does it travel somewhere else?” This is called radiation or referral.
- Radiating Pain: Pain that travels. Heart attack pain can radiate to the jaw, neck, or back. A herniated disc in the lower back can cause pain that radiates down the leg (sciatica).
- Referred Pain: This is when a problem in one place causes pain in another. A good example is gallbladder pain, which is often felt in the right shoulder blade.
Understanding location and radiation is like getting the map to the mystery. It tells you where to focus your physical exam and what body systems might be involved.
D is for DURATION – How Long Has This Been Going On?
The Length of the Story
Duration answers: How long does each episode last? Once you know when it started (onset), you need to know the pattern of each individual occurrence.
- Seconds: A quick, stabbing pain that comes and goes in a flash.
- Minutes to Hours: A typical migraine headache or an angina episode might last this long.
- Days to Weeks: A viral infection or a severe muscle injury.
- Constant: Pain that is always there, 24/7, without a break.
Constant vs. Intermittent
You must clarify: “Is it there all the time, or does it come and go?”
- Constant Symptoms: This suggests an ongoing process. A tumor, a chronic infection, or persistent inflammation.
- Intermittent Symptoms: This suggests triggers. Pain that comes with certain movements (like a torn cartilage) or at certain times of day.
Duration helps you understand the nature of the illness. Is it a brief, repeating event? Or is it a continuous, unending problem? This clue helps separate different types of conditions.
C is for CHARACTER – What Does It Feel Like?
Describing the Indescribable
Character is about the quality of the symptom. Since you cannot feel what the patient feels, you need them to describe it. You ask: “What does it feel like? Can you describe it in your own words?” Encourage them to use similes or metaphors.
Here are common “characters” of pain and what they might mean:
- Sharp, Stabbing, Knife-like: Often from injury to body surface tissues (like a cut) or something serious like a perforated ulcer or pleurisy.
- Dull, Aching: Common with deep, chronic problems like arthritis, a slow-growing tumor, or a muscle ache.
- Burning: Think nerve pain (like sciatica or shingles) or acid reflux (heartburn).
- Throbbing, Pulsating: Often linked to blood flow. A migraine or an abscess can throb with the heartbeat.
- Pressure, Squeezing, Heaviness: The classic description for cardiac chest pain (angina or heart attack).
- Cramping, Colicky: Comes in waves. Typical for organs trying to push something through, like the intestine (gas, diarrhea) or the uterus (menstrual cramps).
Beyond Pain: Character of Other Symptoms
Character is not just for pain. Apply it to anything:
- A cough: Is it dry and hacking? Or wet and productive with phlegm?
- Dizziness: Is it a feeling of spinning (vertigo) or lightheadedness?
- Nausea: Is it a queasy feeling or a urgent need to vomit?
The character is the witness’s description of the suspect. “He was tall with a red hat” is very different from “She had a loud, booming voice.” It points you in a specific direction.
A is for AGGRAVATING FACTORS – What Makes It Worse?
Identifying the Triggers
Aggravating factors are the triggers. You ask: “What makes your symptom worse? Is there anything you do that brings it on or intensifies it?”
This is a powerful clue because it often points directly to the cause.
- Chest pain that gets worse with physical exertion or stress → points to the heart.
- Abdominal pain that is worse after eating fatty foods → points to the gallbladder.
- Headache that gets worse with bright lights or loud sounds → common for migraines.
- Back pain that worsens with bending or lifting → suggests a musculoskeletal issue.
- Shortness of breath that worsens when lying flat → can be a sign of heart failure.
The Power of Specificity
Do not accept vague answers. Push for specifics.
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- Patient: “Moving makes it worse.”
- You: “What kind of movement? Walking? Turning your head? Taking a deep breath?”
- Patient: “Food makes my stomach hurt.”
- You: “What type of food? Spicy? Dairy? Large meals?”
Finding the aggravating factor is like finding out what makes the alarm go off. It helps you understand the mechanism of the disease and gives you one of the first treatment ideas: avoid the trigger.
R is for RELIEVING FACTORS – What Makes It Better?
Discovering Natural Solutions
This is the flip side of “Aggravating.” You ask: “What makes it better? Have you found anything that helps, even a little?”
Patients often try things on their own before seeing you. Their successes and failures are valuable data.
- Chest pain that gets better with rest → again, points to cardiac issues.
- Heartburn that improves with antacids → confirms acid reflux.
- Joint pain that feels better with heat and gentle movement → suggests osteoarthritis.
- Headache that improves in a dark, quiet room → supports a migraine diagnosis.
- Pain that is not relieved by anything, even strong painkillers → is a serious red flag.
What Have They Tried?
Always ask: “Have you taken any medication for this, prescription or over-the-counter? Did it help?” A patient with a migraine who got no relief from usual migraine medication is telling you something important. A patient whose back pain is completely relieved by ibuprofen is telling you something else.
Relieving factors are your first look at what might work for treatment. They are the patient’s own small experiment, giving you hints about what therapies might be effective.
T is for TIMING – Is There a Pattern?
The Rhythm of the Symptom
Timing looks at the pattern over time. It combines onset and duration but looks at the bigger picture. You ask: “Is there a pattern to when it happens?”
- Time of Day: Does it always happen in the morning (like stiffness from rheumatoid arthritis)? At night (like acid reflux when lying down)? After meals?
- Relation to Menstrual Cycle: For people who menstruate, many symptoms (headaches, mood changes, pain) can be tied to the hormonal cycle.
- Frequency: How often does it happen? Once a day? Three times a week? Only on weekends?
The Course Over Time
Also ask: “How has it changed since it first started? Is it getting better, getting worse, or staying the same?”
- Progressively Worse: This is a major concern for serious, growing, or spreading problems.
- Improving: Suggests a self-limiting illness or that something the patient is doing is helping.
- Unchanging: Could be a stable, chronic condition.
Timing reveals the rhythm of the symptom. An event that happens every full moon is different from one that happens at random. A symptom with a clear pattern is easier to understand and address than one that is completely random.
S is for SEVERITY – How Bad Is It?
Measuring the Unmeasurable
Severity is about the intensity of the symptom. Since we cannot measure pain or nausea with a ruler, we use scales. The most common is the 0 to 10 Scale.
- 0 means no symptom at all.
- 10 means the worst imaginable version of that symptom.
You ask: “On a scale of 0 to 10, where 0 is none and 10 is the worst you can imagine, how would you rate your [pain/nausea/etc.] right now? What about at its worst? What about at its best?”
Why Severity Matters
Severity is not just a number. It has several key jobs:
- Triage: It helps you decide how urgent the problem is. A severity of 10/10 crushing chest pain is an emergency. A 2/10 occasional ache is not.
- Tracking: It gives you a baseline. After you start treatment, you can ask again. “Is your pain still a 7? Or has it gone down to a 3?” This measures if your treatment is working.
- Functional Impact: This is the most important question of all: “How is this affecting your daily life?”
- Can you still go to work?
- Can you sleep through the night?
- Can you play with your kids or walk your dog?
A 5/10 pain that stops someone from working is often more “severe” in a real-life sense than an 8/10 pain that comes and goes quickly without changing their function. Severity connects the medical symptom to the human life.
Putting It All Together – OLD CARTS Example
A Case Example: The Case of Mr. Jones’ Chest Pain
Let’s see OLD CARTS work on a real (simplified) case.
- You: “Mr. Jones, tell me about this chest pain.”
- Mr. Jones: “It started about two hours ago, Doc.”
- You (Onset): “Was it sudden?” “Yes, just hit me.” “What were you doing?” “Watching TV, just relaxing.”
- You (Location): “Can you point to where it hurts?” He puts his fist on the center of his chest. “Does it go anywhere else?” “Yeah, into my jaw and down my left arm a bit.”
- You (Duration): “Is it constant, or does it come and go?” “It’s been constant since it started.”
- You (Character): “What does it feel like?” **”Like an elephant is sitting on my chest, just heavy pressure.”
- You (Aggravating): “Does anything make it worse?” “Taking a deep breath makes it a little sharper.”
- You (Relieving): “Does anything make it better?” “No, nothing. I tried an antacid, did nothing.”
- You (Timing): “Has it changed in the last two hours?” “It seems to be getting a little heavier.”
- You (Severity): “On a scale of 0 to 10?” “Right now, an 8. It’s making me really sweaty and scared.”
In less than a minute, OLD CARTS has painted a classic picture of a possible heart attack: Sudden onset, central chest pressure radiating to jaw/arm, constant, worsening, severe, unrelieved by antacids. This triggers an immediate emergency response.
Now, imagine if his answers were: “It’s a sharp stabbing in my left side that comes for a second when I twist. Started yesterday. No radiation. Rest makes it better. It’s a 3/10.” That sounds musculoskeletal, like a muscle strain. Two very different stories, guided by the same checklist.
Making It a Natural Conversation
OLD CARTS is a checklist in your mind, not a script. You don’t say, “Now for the Aggravating Factors…” You weave the questions naturally:
- “So it started yesterday afternoon while you were gardening? (Onset) And it’s here in your lower back? (Location) What does it feel like – more of an ache or a sharp pain? (Character)…”
Practice makes it flow. Soon, you will gather all this information without the patient even noticing your structure.
OLD CARTS vs. OPQRST
You might have heard of another acronym used for gathering a patient’s history: OPQRST. It’s a common tool, especially in emergency medical services (EMS) and some fast-paced clinical settings. With two similar frameworks available, a fair question is: which one is better? The truth is, both are excellent systems for organizing your questions. The choice often comes down to personal preference, clinical setting, and the specific details you find most helpful to remember.
Let’s break down OPQRST. It stands for:
- Onset
- Provocation/Palliation (what brings it on or makes it better)
- Quality (the same as Character)
- Region/Radiation (the same as Location)
- Severity
- Time (covering both Duration and Timing patterns)
As you can see, there is significant overlap. Both ensure you ask about when it started, what it feels like, where it is, and how bad it is. The main differences are in the grouping and emphasis of details.
OLD CARTS is often favored in comprehensive clinical settings, like a primary care office, a specialist’s clinic, or an inpatient ward, because it is slightly more detailed and separates key concepts. By having Aggravating and Relieving as two distinct letters, it reminds you to explicitly ask about both triggers and what the patient has tried. It also separates Duration (length of one episode) from Timing (the overall pattern), which can be crucial for complex conditions.
OPQRST, on the other hand, is streamlined and powerful for rapid assessment. Combining provocation and palliation into one letter (“P”) and time into one letter (“T”) makes it faster to recall in a high-pressure situation. This efficiency is why it’s a staple in pre-hospital care and triage environments where speed is critical.
So, which should you use? The best answer is: learn one system deeply. The ultimate goal is not to memorize an acronym, but to internalize a structured approach to questioning. Whether you choose OLD CARTS or OPQRST, consistently using its framework will ensure you never miss a key part of the history. Many clinicians start with OLD CARTS for its thoroughness and later adapt their own hybrid mental model. The most important thing is that you have a reliable, repeatable method to uncover the full patient story every single time.
Conclusion: OLD CARTS – More Than a Mnemonic, A Foundation of Care
OLD CARTS is not just a silly word to remember for an exam. It is the foundation of clinical reasoning. It is the system that ensures you get the full story. In a world of advanced technology, MRI machines, genetic tests, and instant labs, the patient’s story is still the most important diagnostic tool you have. Over 70-80% of diagnoses can be made from the history alone.
By using OLD CARTS, you show your patients that you are listening. You are thorough. You care about the details of their experience. This builds trust, which is the most powerful medicine of all.
So, for every patient, for every symptom, be a detective. Use your OLD CARTS checklist. Uncover the story. Because behind every symptom is a person waiting for you to understand, so you can help them find their way back to health.
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Dr. Connor Yost is an Internal Medicine resident at Creighton University School of Medicine in Arizona and an emerging leader in clinical innovation. He currently serves as Chief Medical Officer at Skriber, where he helps shape AI-powered tools that streamline clinical documentation and support physicians in delivering higher-quality care. Dr. Yost also works as a Strategic Advisor at Doc2Doc, lending his expertise to initiatives that improve financial wellness for physicians and trainees.
His professional interests include medical education, workflow redesign, and the responsible use of AI in healthcare. Dr. Yost is committed to building systems that allow clinicians to spend more time with patients and less on administrative tasks. Outside of medicine, he enjoys photography, entrepreneurship, and family life.




