Introduction: Seeing the Whole Person
When a patient walks into your office, what do you see? You see their symptoms. You hear their complaints. But is that the whole story? For many years, medicine focused mostly on the body. If someone had back pain, we looked at their spine. If someone felt sad, we looked at their brain chemistry. This is the bio part – the biology of illness. But people are not just bodies. They have thoughts, feelings, jobs, families, and cultures. A back injury might hurt more if a person is stressed about losing their job. A person might not get better from an illness if they can’t afford their medicine or have no one to help them at home. This bigger picture is what the Biopsychosocial Model is all about. It is a way of understanding health and sickness that looks at three equally important parts: Biological, Psychological, and Social. A Biopsychosocial Assessment is the tool we use to gather this complete picture. It’s like being a detective for health. You are not just asking “what is the disease?” You are asking “why is this person sick, at this time, and what is stopping them from getting better?”
This guide will explain each part of the model. It will show you how to do a full assessment. And it will give you real examples to use in your work with clients.
Why It Matters: More Than Just a Diagnosis
Using only a biological model is like fixing a car by only looking at the engine. But what if the problem is bad fuel, or a driver who is too tired to operate it safely? The car is a system. A human being is a much more complex system. The Biopsychosocial model helps us avoid mistakes. It helps us understand why a treatment that works in a textbook might not work for the person in front of us. For example, giving exercise plans for diabetes is good biological advice. But if the patient lives in an unsafe neighborhood with no parks, they cannot follow the advice. That is a social barrier. Another patient might believe that “real men don’t go to doctors,” so they delay care until their illness is severe. That is a psychological and social belief. By doing a full assessment, you create a treatment plan that has a real chance of working. You build trust with the patient because they feel heard. You address the true causes of their suffering, not just the symptoms. This leads to better outcomes, fewer hospital visits, and more satisfied patients and providers.
The “Bio” – Biological Factors
The biological part is what we are most trained in. It is about the physical body. This includes the disease itself, but also genetics, body chemistry, brain function, and overall physical health. You are looking for how the body is breaking down or reacting. This is the foundation of your assessment, but it is not the whole building.
What to Ask and Look For: Start with the chief complaint. What brought the person in? Then, take a full history of the present illness. When did it start? What makes it better or worse? Get a detailed past medical history: surgeries, hospital stays, major illnesses. List all current medications and doses, including over-the-counter drugs and supplements. Do a full review of body systems. Ask about family medical history. What did their parents or grandparents suffer from? Note any allergies. Look at their basic health behaviors: sleep patterns, diet, exercise, use of substances like tobacco, alcohol, or drugs. The physical exam and any lab tests or scans (like X-rays or MRIs) all feed into this biological section. You are building a map of the person’s physical state.
Example in Practice – Chronic Pain: Let’s take a patient, Maria, age 58, with chronic lower back pain. The biological assessment finds she had a discectomy surgery 5 years ago. An MRI shows mild arthritis in her spine. She takes ibuprofen daily, which is causing some stomach irritation. She sleeps poorly because the pain wakes her up. She has stopped her daily walks. Her father also had severe back problems. This is all crucial biological data. A treatment based only on this might include a different pain medication, a referral to a pain clinic, or physical therapy. But if we stop here, we miss key pieces.
Connecting Biology to the Rest: Biology is never in a vacuum. Maria’s poor sleep makes her pain feel worse the next day. This is a bio-psycho link—the physical affects the mental. The fact that she has stopped walking means she is losing muscle strength, which makes her spine less supported. This is a bio-behavioral link. The biological factors are real and powerful. They create real limits and real suffering. Your job is to document them thoroughly as the first piece of the puzzle. Always remember that this physical experience is happening to a person who has thoughts and a life.
The “Psycho” – Psychological Factors
This part is about the mind, emotions, and personality. It is how the person’s inner world interacts with their health. Thoughts, feelings, beliefs, and coping skills can all make a disease better or worse. Psychological stress can actually change body chemistry, raising blood pressure or weakening the immune system. Understanding this is key to helping the patient help themselves.
What to Ask and Look For: Explore the person’s mental health history. Have they ever been diagnosed with depression, anxiety, PTSD, or another condition? Have they seen a therapist or counselor before? Assess their current mental state. How is their mood? Are they feeling sad, nervous, angry, or hopeless? What is their attitude towards their illness? Do they believe they can get better? What are their biggest fears? Look at their coping mechanisms. How do they handle stress? Do they talk to someone, exercise, meditate, or do they shut down, use substances, or get angry? Assess their cognitive function—memory, concentration, and ability to make decisions. Also, understand their personality style. Are they a fighter, or do they feel helpless? Their beliefs about health and medicine are also here.
Example with Maria – The Mind’s Role: When we talk to Maria about the psychological factors, a new story emerges. She tells us she feels defeated. She says, “My body is broken, and I’ll never be the grandmother who can play with her grandkids.” This is a powerful negative belief. She is afraid to move because she thinks she will cause more damage. She reports feeling anxious every time her pain flares up, worrying it means she needs another surgery. She has low motivation because she feels hopeless. She used to cope by gardening, but she has given that up. Now, she just sits and worries. These psychological factors are making her biological pain worse. The fear and inactivity create a cycle where her muscles weaken, her mood drops, and her pain perception increases.
The Power of Beliefs and Coping: Maria’s example shows how psychology works. Catastrophic thinking (“I’m broken forever”) leads to fear. Fear leads to avoidance (not walking). Avoidance leads to physical deconditioning, which leads to more pain. It’s a vicious cycle. A good assessment identifies this cycle. It also looks for strengths. Maybe Maria has been resilient in the past when facing other challenges. You can remind her of that strength. The goal is to understand her mental landscape. You need to know if she has clinical depression that needs treatment. You need to know if her coping skills are helping or hurting. This information guides you to add psychological tools to the treatment plan, like cognitive-behavioral therapy for pain, mindfulness training, or a referral to a psychologist.
The “Social” – Social Factors
This is the person’s world outside their skin. It is the context of their life. Health does not happen in a doctor’s office; it happens in homes, jobs, and communities. Social factors can be the biggest drivers of health outcomes. They can also be the biggest barriers to getting better. You cannot prescribe a medication that needs refrigeration to a person who is homeless. You cannot tell someone to rest if they have three jobs and three kids to care for.
What to Ask and Look For: Start with relationships. What is their marital or partnership status? Do they have supportive friends or family? Or are they isolated? Look at their employment and finances. Do they have a job? Is it stressful? Do they have insurance? Can they afford their rent, food, and medicines? Assess their living situation. Is their home safe? Do they have stairs they cannot climb? What is their neighborhood like? Culture and religion are huge social factors. What are their health beliefs? Do they use traditional healing practices? What is their level of education? How does it affect their health understanding? Look at their daily responsibilities—are they a caregiver for a sick spouse or young children? Finally, assess their access to care. Can they get transportation to appointments? Do they have a reliable phone to schedule follow-ups?
Example with Maria – Life Context: Exploring Maria’s social world gives us the final, critical piece. She is a widow who lives alone. Her adult children live in another state. She is socially isolated, which makes her depression worse. She worked as a cleaner, but her back pain forced her to stop. She is now on disability, which gives her a very small, fixed income. She is worried about paying for new medications. Her apartment has a flight of stairs that she struggles with. She doesn’t drive, and the bus stop is two blocks away, which feels like a long walk on bad pain days. Her primary social contact is her church group, but she hasn’t attended in months because she can’t sit through the service. These are not medical problems, but they are health problems.
Social Factors as Cause and Effect: For Maria, social factors are both a cause of stress and a consequence of her illness. Losing her job (social) hurt her income and her sense of purpose (psychological). Living alone (social) means no one is there to encourage her to go for a walk or help with heavy chores. The stairs (social/environmental) are a direct barrier to her leaving her home. A treatment plan that ignores this is doomed. Telling her to “join a water aerobics class” is useless if she can’t afford it, can’t get there, and is too isolated to go alone. The social assessment tells you what resources she needs: perhaps a referral to social work to check on benefits, a recommendation for a home health aide for chores, or connection to a volunteer visitor program to reduce isolation.
Putting It All Together: Conducting the Assessment
You don’t do this assessment in three separate boxes. You weave it into one conversation. You start with, “Tell me what’s been going on.” As they tell their story, you listen for clues in all three areas. You might move from biology to psychology to social in a natural flow.
The Flow of the Interview:
Start open-ended. “What brought you in today?” Let the patient talk. Then, gently guide them. “You mentioned the pain started after your mother passed away. Tell me more about that time.” (This connects bio and psycho/social). “When the pain is bad, what goes through your mind?” (Psychological). “What does a typical day look like for you now?” (This reveals social and behavioral factors). “What are your biggest worries about this?” (Psycho and social). “What would getting better look like for you?” (This assesses goals and beliefs). Your job is to connect the dots. You are making a web, not a list.
Documenting Your Findings:
Your note should reflect the model. After the history and physical, you can have a “Biopsychosocial Formulation” section.
For Maria, it might read: “Biological: Chronic LBP s/p discectomy, lumbar arthritis, medication side effects, poor sleep, deconditioned. Psychological: Symptoms of major depression (low mood, anhedonia, hopelessness). Catastrophic thinking and fear-avoidance behavior regarding pain. Coping skills currently ineffective. Social: Lives alone, socially isolated. Limited finances on fixed disability income. Environmental barriers (stairs, distance to transit). Loss of work role and social connection to church.
Formulation: Maria’s chronic pain and disability are maintained by a cycle of biological deconditioning, psychological distress/depression, and social isolation/environmental barriers. Addressing only one area is unlikely to succeed.” This formulation directly leads to a multidimensional plan.
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Creating an Integrated Treatment Plan:
The plan must touch on all three areas.
For Maria: Biological: Switch to a safer NSAID, consider topical pain reliever. Referral to Physical Therapy for a home-based, gentle strengthening program. Psychological: Start antidepressant medication and/or refer to therapist skilled in CBT for chronic pain and depression. Educate on pain cycle and fear-avoidance. Social: Referral to social worker to assess for in-home support services and transportation assistance. Connect with church to explore visitations or virtual participation. Consider volunteer “friendly caller” program. This plan attacks the problem from all sides. Each professional on the team understands their role based on the shared formulation.
Conclusion
The Biopsychosocial model is not just a theory. It is a practical guide to being a better, more effective, and more compassionate professional. It reminds us that we treat people, not diseases. By taking the time to ask about biology, psychology, and social life, you see the true picture of your patient’s health. You will find the real barriers to healing. You will also find hidden strengths you can build upon. It might seem like a lot of work, but it saves time and resources in the long run by creating plans that actually work. It prevents frustration for both you and the patient. Start your next assessment with a curious mind. Look beyond the symptom. Listen for the story. Be the detective who puts all the clues together. When you do, you will not just be managing a disease—you will be helping a whole person move toward a healthier, more fulfilling life. That is the heart of true healing.
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Dr. Connor Yost is an Internal Medicine resident at Creighton University School of Medicine in Arizona and an emerging leader in clinical innovation. He currently serves as Chief Medical Officer at Skriber, where he helps shape AI-powered tools that streamline clinical documentation and support physicians in delivering higher-quality care. Dr. Yost also works as a Strategic Advisor at Doc2Doc, lending his expertise to initiatives that improve financial wellness for physicians and trainees.
His professional interests include medical education, workflow redesign, and the responsible use of AI in healthcare. Dr. Yost is committed to building systems that allow clinicians to spend more time with patients and less on administrative tasks. Outside of medicine, he enjoys photography, entrepreneurship, and family life.




